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The best source of the Omega-3 fatty acids EPA and DHA is seafood especially fatty fish. EPA and DHA are found in various oils and supplements and may be enriched in certain foods. In most people intakes of EPA and DHA are too low. Consequently, status of EPA and DHA in the body is low. Increasing intake of EPA and DHA leads to their incorporation into blood, cells and tissues in a dose-, time- and location-dependent manner. Incorporation of EPA and DHA into cell membranes affects numerous cellular events that alter cell and tissue responsiveness in a way that promotes improved health.